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Hormonal Imbalances: Fluctuations in estrogen and progesterone are the most frequent culprits. This can be influenced by:
- Stress: Chronic stress elevates cortisol, disrupting reproductive hormones.
- Significant Weight Changes: Rapid weight loss/gain or very low body weight (e.g., in athletes or eating disorders) can halt ovulation.
- Polycystic Ovary Syndrome (PCOS): A common hormonal disorder causing irregular cycles, ovarian cysts, and often excess androgen.
- Thyroid Disorders: Both hyperthyroidism and hypothyroidism can impact cycle regularity.
- Perimenopause: The transition to menopause often brings cycle irregularity.
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Lifestyle Factors:- Excessive Exercise: Intense physical activity can suppress ovulation.
- Poor Nutrition: Deficiencies can affect hormonal production.
- Sleep Disruptions: Affects hormone regulation.
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Medical Conditions:- Uterine Fibroids or Polyps: Benign growths causing heavy or irregular bleeding.
- Pelvic Inflammatory Disease (PID): Infection impacting reproductive organs.
- Endometriosis: Tissue similar to the uterine lining grows outside the uterus, causing pain and irregular bleeding.
- Primary Ovarian Insufficiency (POI): Early loss of ovarian function before age 40.
- Chronic Diseases: Unmanaged diabetes, celiac disease.
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Medications: Certain drugs, like some antipsychotics, chemotherapy, blood thinners, and hormonal treatments (including starting/stopping birth control), can cause irregularity.
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Breastfeeding: Prolactin, the milk-producing hormone, suppresses ovulation, leading to irregular or absent periods.